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NIRx Medical Technologies
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NIRx Medical Technologies
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Proteintech
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NIRx Medical Technologies
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Image Search Results
Journal: Neuron
Article Title: Polyglutamine-expanded huntingtin exacerbates age-related disruption of nuclear integrity and nucleocytoplasmic transport
doi: 10.1016/j.neuron.2017.03.027
Figure Lengend Snippet: (A, B) Immunofluorescence of polyQ Htt (red) and Gle1 (green) in cortical sections of (A) HttQ7/Q7, HttQ7/Q175 and HttQ175/Q175 mice of indicated ages and (B) 3-month-old control and R6/2 mice. Nuclei were stained with DAPI. (C) Percentage of nuclear polyQ aggregates positive for Gle1, in mice of indicated genotypes and ages. Data are shown as mean ± SEM. **: P<0.01, chi-square test. 100 cells were counted per genotype and age. A, B: Arrowheads point to Gle1/polyQ Htt nuclear co-localization.
Article Snippet: Antibodies The following primary antibodies were used for immunofluorescence experiments: Anti-Huntingtin Protein Antibody, clone mEM48, MAB-5374, Millipore (1:500); lamin B1 Antibody (S-20), sc-30264, Santa Cruz (1:5000); lamin B1 Antibody, 12987-1-AP,
Techniques: Immunofluorescence, Staining
Journal: Neuron
Article Title: Polyglutamine-expanded huntingtin exacerbates age-related disruption of nuclear integrity and nucleocytoplasmic transport
doi: 10.1016/j.neuron.2017.03.027
Figure Lengend Snippet: KEY RESOURCES TABLE
Article Snippet: Antibodies The following primary antibodies were used for immunofluorescence experiments: Anti-Huntingtin Protein Antibody, clone mEM48, MAB-5374, Millipore (1:500); lamin B1 Antibody (S-20), sc-30264, Santa Cruz (1:5000); lamin B1 Antibody, 12987-1-AP,
Techniques: Knock-In, Software, Imaging